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Treatment

Medication for ADHD

Medication does not take ADHD away and does not change your personality. What it does do is create space. Medication is never compulsory: you decide.

What medication does

Medication for ADHD works through the substances dopamine and noradrenaline in the brain. What happens in the brain

One of the most thoroughly researched treatments in psychiatry

70–80%

Research shows that symptoms clearly decrease in about 70 to 80% of adults.

Medication does not make you smarter and does not teach you new skills. That is why we usually combine medication with psychoeducation and cognitive behavioural therapy.

The medicines

  • First choice

    Methylphenidate

    Our medicine of first choice, in short-acting and long-acting forms.
  • Often the second step

    Dexamfetamine and lisdexamfetamine

    A stimulant alternative if methylphenidate does not help enough or is not suitable.
  • Non-stimulant

    Atomoxetine

    Works gradually, with its full effect after a number of weeks, and provides cover throughout the day. An option if you have anxiety or sleep problems, or if stimulants are not suitable.

How we adjust your dose

  1. Measuring

    Beforehand, we measure your blood pressure, heart rate and weight.
  2. Starting low

    You start on a low dose.
  3. Step by step

    Every one to two weeks, we evaluate the effect and any side effects, and adjust the dose if needed.
  4. The right dose

    Together we look for the dose that suits you best.
  5. Check-ups and handover

    Once your dose is stable, check-ups take place at longer intervals. At completion, your GP can take care of your repeat prescription in consultation.

Side effects

Side effects are usually mild and often disappear within one to two weeks. Examples are a reduced appetite, difficulty falling asleep, headache, a dry mouth, a slightly higher heart rate or blood pressure, or a dip when the medication wears off.

Always report side effects. They are almost never a reason to stop completely; a different dose, a different time or a different medicine often helps.

Medication in daily life

  • Driving

    Do not drive while your dose is being adjusted or after a change in dose. Once your dose is stable and you have no side effects that affect driving, you are in principle allowed to drive. Since 1 April 2026, you no longer need a separate medical assessment for ADHD by the CBR (the Dutch driving licence authority).
  • Travelling

    Methylphenidate and (lis)dexamfetamine fall under the Dutch Opium Act (Opiumwet). Within the Schengen area you need a Schengen certificate (Schengenverklaring), and outside it a medical statement in English. Arrange this four to six weeks in advance and carry your medication in its original packaging in your hand luggage. How to arrange it with the CAK (in Dutch) (opens in a new window)
  • Alcohol

    We advise against alcohol in combination with ADHD medication. If you take dexamfetamine or lisdexamfetamine, do not drink alcohol if you are going to drive.
  • Wanting children or pregnancy

    Always discuss a wish to have children or a pregnancy with your practitioner.

You decide

Medication is never compulsory and is only prescribed if it suits you. A trial period is possible, and you can stop at any time in consultation with us.

Questions about medication

Sources

Treatment

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For an assessment and treatment with us, you need a referral from your GP. On the Registration page you can read how this works.